Computational Model for Early Cardiac Looping
نویسندگان
چکیده
منابع مشابه
Biophysical mechanisms of cardiac looping.
During early embryogenesis, the heart is a single, relatively straight tube which bends and twists (loops) rightward to create the basic plan of the mature heart. Despite intensive study for many decades, the biophysical mechanisms which drive and regulate cardiac looping have remained poorly understood. This review discusses, from a historical perspective, studies of looping mechanics and vari...
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Alcohol-induced congenital heart defects are frequently among the most life threatening and require surgical correction in newborns. The etiology of these defects, collectively known as fetal alcohol syndrome, has been the focus of much study, particularly involving cellular and molecular mechanisms. Few studies have addressed the influential role of altered cardiac function in early embryogene...
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The morphogenetic process of cardiac looping transforms the straight heart tube into a curved tube that resembles the shape of the future four-chambered heart. Although great progress has been made in identifying the molecular and genetic factors involved in looping, the physical mechanisms that drive this process have remained poorly understood. Recent work, however, has shed new light on this...
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متن کاملEthanol exposure alters early cardiac function in the looping heart: a mechanism
29 Alcohol-induced congenital heart defects (CHDs) are frequently among the most 30 life-threatening and require surgical correction in newborns. The etiology of these defects, 31 collectively known as Fetal Alcohol Syndrome (FAS), has been the focus of much study, 32 particularly involving cellular and molecular mechanisms. Few studies have addressed 33 the influential role of altered cardiac ...
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ژورنال
عنوان ژورنال: Annals of Biomedical Engineering
سال: 2006
ISSN: 0090-6964,1573-9686
DOI: 10.1007/s10439-006-9152-2